Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348423 | 0.92 | NR1I2 (0.35) | PDCD1CD274ROCK2JAK2NR1I2 | |
| SCHEMBL31068244 | 0.84 | CRBN (0.47) | PDCD1CD274 | |
| SCHEMBL29348744 | 0.84 | CRBN (0.47) | PDCD1CD274 | |
| SCHEMBL29348382 | 0.77 | JAK2 (0.43) | JAK2GRM2 | |
| SCHEMBL31068309 | 0.76 | DDB1 (0.47) | PDCD1CD274NR1I2KCNH2GRM2 | |
| SCHEMBL29348496 | 0.74 | DRD2 (0.32) | GRM2 | |
| SCHEMBL29348204 | 0.74 | F10 (0.37) | — | |
| SCHEMBL29348405 | 0.73 | MET (0.31) | — | |
| SCHEMBL29348378 | 0.73 | JAK2 (0.40) | JAK2GRM2 | |
| SCHEMBL29348508 | 0.73 | GRM2 (0.33) | PDCD1CD274GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |