Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PER2 | O15055 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348754 | 0.84 | HSD11B1 (0.43) | SMN1; SMN2MITFALDH1A1USP2CYP2B6 | |
| SCHEMBL2697747 | 0.83 | CYP2B6 (0.53) | SMN1; SMN2MITFPER2ALDH1A1CYP2B6 | |
| SCHEMBL12581558 | 0.80 | TSHR (0.38) | SMN1; SMN2MITFALDH1A1LMNAKMT2A | |
| SCHEMBL20476032 | 0.79 | KMT2A (0.39) | SMN1; SMN2MITFALDH1A1LMNACYP2B6 | |
| SCHEMBL2695770 | 0.78 | CYP2B6 (0.50) | SMN1; SMN2MITFPER2ALDH1A1LMNA | |
| SCHEMBL3708789 | 0.71 | CYP2B6 (0.42) | SMN1; SMN2ALDH1A1CYP2B6KMT2AMEN1 | |
| SCHEMBL122141 | 0.70 | BRD4 (0.41) | SMN1; SMN2MITFPER2ALDH1A1LMNA | |
| SCHEMBL868298 | 0.69 | MITF (0.40) | SMN1; SMN2MITFPER2ALDH1A1LMNA | |
| SCHEMBL1625501 | 0.69 | MITF (0.40) | SMN1; SMN2MITFPER2ALDH1A1LMNA | |
| SCHEMBL16281888 | 0.69 | MITF (0.40) | SMN1; SMN2MITFPER2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |