⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570744 | 0.69 | — | — | |
| SCHEMBL6906143 | 0.69 | — | — | |
| SCHEMBL28032286 | 0.67 | MEN1 (0.30) | — | |
| SCHEMBL4650148 | 0.67 | — | — | |
| SCHEMBL27777052 | 0.67 | — | — | |
| SCHEMBL22308091 | 0.67 | — | — | |
| SCHEMBL24667243 | 0.67 | — | — | |
| SCHEMBL28009488 | 0.67 | — | — | |
| SCHEMBL27724806 | 0.67 | — | — | |
| Iodide SCHEMBL27607763 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |