SCHEMBL29350757

SCHEMBL29350757

Nc1nc2nc[nH]c2c(=O)n1P(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 1/20 0.44
▸ DPP4 P27487 1/20 0.41
▸ GDA Q9Y2T3 2/20 0.40
▸ PDPK1 O15530 1/20 0.40
▸ CDK2 P24941 3/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MGMT P16455 3/20 0.36
▸ MAP3K5 Q99683 1/20 0.36
▸ CYP1A2 P05177 2/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ PI4KA P42356 2/20 0.34
▸ PI4K2B Q8TCG2 2/20 0.34
▸ PI4K2A Q9BTU6 2/20 0.34
▸ PI4KB Q9UBF8 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ DRD3 P35462 1/20 0.34
▸ XDH P47989 1/20 0.34
▸ LRRK2 Q5S007 1/20 0.34
▸ ATAD2 Q6PL18 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
B-D-Galactose SCHEMBL28566641 0.82 LMNA (0.36) PNPALDH1A1CYP1A2LMNA
Phosphoric Acid SCHEMBL27758691 0.82 PNP (0.44) PNPDPP4GDAPDPK1CDK2
Phosphoric Acid SCHEMBL27758697 0.82 PNP (0.44) PNPDPP4GDAPDPK1CDK2
Demannose SCHEMBL29025805 0.81 DPP4 (0.32) PNPDPP4GDAPDPK1MGMT
Phosphoric Acid SCHEMBL27779727 0.81 PNP (0.43) PNPDPP4GDAPDPK1CDK2
Phosphoric Acid SCHEMBL27780172 0.81 PNP (0.43) PNPDPP4GDAPDPK1CDK2
SCHEMBL16767176 0.78 PNP (0.41) PNPDPP4GDAPDPK1CDK2
SCHEMBL2983851 0.78 PNP (0.49) PNPDPP4GDAPDPK1CDK2
Water SCHEMBL9697811 0.76 PNP (0.47) PNPDPP4GDAPDPK1CDK2
SCHEMBL13733587 0.76 HPRT1 (0.35) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325929-A Escherichia coli for producing fucosyllactose by using mannose and application thereof 天津科技大学 2024-07-12 — — CN claimed
CN-118207191-A Methionine aminopeptidase mutant, escherichia coli engineering bacteria and application 山东合成远景生物科技有限公司 2024-06-18 — — CN claimed
CN-118207145-A Engineering strain for producing 2' -fucosyllactose, construction method and application 山东合成远景生物科技有限公司 2024-06-18 — — CN claimed
CN-115466707-A Lactococcus lactis for producing 2' -fucosyllactose and application thereof 天津科技大学 2022-12-13 — — CN claimed
CN-114276971-A Recombinant escherichia coli for synthesizing 2' -fucosyllactose by utilizing mannose and application thereof 天津科技大学 2022-04-05 — — CN claimed
CN-113957027-A Genetic engineering bacterium for improving yield of lactoyl-N-fucohexaose and production method thereof 江南大学 2022-01-21 — — CN claimed
CN-118325929-A Escherichia coli for producing fucosyllactose by using mannose and application thereof 天津科技大学 2024-07-12 — — CN disclosed
CN-118207191-A Methionine aminopeptidase mutant, escherichia coli engineering bacteria and application 山东合成远景生物科技有限公司 2024-06-18 — — CN disclosed
CN-118207145-A Engineering strain for producing 2' -fucosyllactose, construction method and application 山东合成远景生物科技有限公司 2024-06-18 — — CN disclosed
CN-114806991-B Engineering escherichia coli for improving fucosyllactose yield and production method thereof 江南大学 2023-08-25 — — CN disclosed
CN-116334025-A RNA polymerase beta subunit mutant and application thereof 天津科技大学 2023-06-27 — — CN disclosed
CN-110662842-B Production method of 3-fucosyllactose using corynebacterium glutamicum 首尔大学校产学协力团 2023-03-21 — — CN disclosed
CN-115786220-A Recombinant strain for producing 2' -fucosyllactose, construction method and application 山东合成远景生物科技有限公司 2023-03-14 — — CN disclosed
CN-115466707-A Lactococcus lactis for producing 2' -fucosyllactose and application thereof 天津科技大学 2022-12-13 — — CN disclosed
CN-114480240-A Genetic engineering bacterium for producing fucosyllactose and production method thereof 江南大学 2022-05-13 — — CN disclosed
CN-114276971-A Recombinant escherichia coli for synthesizing 2' -fucosyllactose by utilizing mannose and application thereof 天津科技大学 2022-04-05 — — CN disclosed
CN-114276971-A Recombinant escherichia coli for synthesizing 2' -fucosyllactose by utilizing mannose and application thereof 天津科技大学 2022-04-05 — — CN disclosed
CN-113957027-A Genetic engineering bacterium for improving yield of lactoyl-N-fucohexaose and production method thereof 江南大学 2022-01-21 — — CN disclosed
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