Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | STAT6 | P42226 | 1/20 | 0.77 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.77 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.77 |
| ▸ | HEXA | P06865 | 5/20 | 0.74 |
| ▸ | HEXB | P07686 | 5/20 | 0.74 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.67 |
| ▸ | AHR | P35869 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amonafide SCHEMBL6255345 | 1.00 | FTO (1.00) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL27226 | 1.00 | FTO (1.00) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL1049714 | 0.99 | FTO (0.97) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL1566668 | 0.99 | FTO (0.97) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL1051955 | 0.99 | FTO (0.97) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL20242315 | 0.94 | FTO (0.88) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL1566374 | 0.93 | FTO (0.86) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL9144516 | 0.93 | FTO (0.86) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL1565520 | 0.93 | FTO (0.86) | FTOCYP2D6POLBMEN1KMT2A | |
| Amonafide SCHEMBL5164837 | 0.92 | FTO (0.84) | FTOCYP2D6POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129074-A2 | INDEXING TECHNIQUES FOR TAGMENTED DNA LIBRARIES | ILLUMINA, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-113956256-B | Matrine D ring structure modified derivative and application thereof in preparation of antitumor drugs | 常州大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113956256-A | Derivative with modified matrine D-ring structure and application of derivative in preparation of antitumor drugs | 常州大学 | 2022-01-21 | — | — | CN | disclosed |