Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429718 | 0.85 | PIM1 (0.49) | KDM4EKMT2AKMONFKB1MAOA | |
| SCHEMBL10746966 | 0.80 | KDM4E (0.40) | KDM4EKMT2AKMOTDP1MAPT | |
| SCHEMBL1088781 | 0.75 | KDM4E (0.67) | KDM4EKMT2ATDP1MAPTRAB9A | |
| SCHEMBL10651674 | 0.75 | MGAM (0.48) | KDM4EKMT2AKMOTDP1MAPT | |
| Hydrochloric Acid SCHEMBL10553456 | 0.73 | KDM4E (0.64) | KDM4EKMT2ATDP1MAPTRAB9A | |
| Benzene SCHEMBL27872024 | 0.73 | KDM4E (0.70) | KDM4EKMT2ATDP1MAPTRAB9A | |
| SCHEMBL10607536 | 0.73 | MGAM (0.46) | KDM4EKMT2AKMOTDP1MAPT | |
| SCHEMBL9756635 | 0.73 | MGAM (0.55) | KDM4EKMT2ATDP1MAPTRAB9A | |
| Methyl Alcohol SCHEMBL28609065 | 0.72 | KDM4E (0.62) | KDM4EKMT2ATDP1MAPTRAB9A | |
| Benzene SCHEMBL27888317 | 0.72 | KDM4E (0.68) | KDM4EKMT2ATDP1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115184478-A | Quantitative analysis method of 70 amino substances in blood plasma based on 'derivatization in fiber' strategy and application thereof | 沈阳药科大学 | 2022-10-14 | — | — | CN | claimed |
| CN-111398497-B | Application of kynurenine in identifying Chinese bee honey and apis mellifera honey | 中国农业科学院蜜蜂研究所 | 2022-08-19 | — | — | CN | claimed |
| CN-114601832-A | Application of kynurenic acid in preparation of medicine for improving HIV-1 related neurocognitive dysfunction | 南方医科大学 | 2022-06-10 | — | — | CN | claimed |
| CN-113984918-A | High performance liquid characteristic spectrum of stir-fried aspongopus or extract thereof, and construction method and application thereof | 天津现代创新中药科技有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110680813-B | Use of naphthoquinone derivatives as IDO1 and/or TDO inhibitors | 北京大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-109863140-B | 3-oxo-2, 6-diphenyl-2, 3-dihydropyridazine-4-carboxamide | 拜耳医药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-115184478-A | Quantitative analysis method of 70 amino substances in blood plasma based on 'derivatization in fiber' strategy and application thereof | 沈阳药科大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-115078588-A | Aspongopus and quality evaluation method of processed product thereof | 江阴天江药业有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111398497-B | Application of kynurenine in identifying Chinese bee honey and apis mellifera honey | 中国农业科学院蜜蜂研究所 | 2022-08-19 | — | — | CN | disclosed |
| CN-114601832-A | Application of kynurenic acid in preparation of medicine for improving HIV-1 related neurocognitive dysfunction | 南方医科大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114601832-A | Application of kynurenic acid in preparation of medicine for improving HIV-1 related neurocognitive dysfunction | 南方医科大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114007600-A | Genetic variation associated with therapeutic response to neurological disorders | 维斯塔津治疗公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113984918-A | High performance liquid characteristic spectrum of stir-fried aspongopus or extract thereof, and construction method and application thereof | 天津现代创新中药科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113984918-A | High performance liquid characteristic spectrum of stir-fried aspongopus or extract thereof, and construction method and application thereof | 天津现代创新中药科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113957061-A | Administration of kynurenine depleting enzymes for tumor therapy | 得克萨斯大学体系董事会 | 2022-01-21 | — | — | CN | disclosed |