Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094226 | 0.83 | LMNA (0.59) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL1088781 | 0.83 | KDM4E (0.67) | MGAMKDM4EKMT2ATDP1MAPT | |
| Hydrochloric Acid SCHEMBL10553456 | 0.81 | KDM4E (0.64) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL2175934 | 0.80 | MGAM (0.64) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL8883056 | 0.79 | KDM4E (0.46) | MGAMKDM4EKMT2ATDP1MAPT | |
| Methyl Alcohol SCHEMBL28609065 | 0.79 | KDM4E (0.62) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL7036195 | 0.78 | KDM4E (0.62) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL7566091 | 0.78 | KDM4E (0.45) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL6391903 | 0.77 | MGAM (0.67) | MGAMKDM4EKMT2ATDP1MAPT | |
| SCHEMBL14610933 | 0.77 | KDM4E (0.60) | MGAMKDM4EKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012004-A1 | TOPICAL USE OF 6-N-BUTYL-1,4,7,10-TETRAHYDRO-4,10-DIOXO-1,7-PHENANTHROLINE-2,8-DICARBOXYLIC ACID DERIVATIVES | ALLERGAN, INC. (US) | 1991-08-22 | — | — | WO | disclosed |