Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162083 | 0.87 | TAAR1 (0.62) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8104290 | 0.84 | TAAR1 (0.60) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11073018 | 0.84 | TAAR1 (0.60) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7404185 | 0.82 | TAAR1 (0.64) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| Formic Acid SCHEMBL27867378 | 0.81 | KEAP1 (0.55) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL244155 | 0.79 | — | — | |
| Alcohol SCHEMBL28201251 | 0.79 | TAAR1 (0.50) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28323221 | 0.77 | TAAR1 (0.62) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL394300 | 0.77 | TAAR1 (0.76) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5386093 | 0.76 | TAAR1 (0.56) | TAAR1KEAP1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294749-B | (S) -1, 3-thiazole phenyl furan thiocarbamate compound and preparation method and application thereof | 华南农业大学 | 2022-01-25 | — | — | CN | disclosed |