SCHEMBL29353346

SCHEMBL29353346

CC[C@H](C)[C@H](NC(=O)CN)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)O)[C@@H](C)CC)[C@@H](C)O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ VIPR1 P32241 3/20 0.53
▸ VIPR2 P41587 4/20 0.50
▸ KISS1R Q969F8 4/20 0.50
▸ GRIN2D O15399 1/20 0.50
▸ GRIN3B O60391 1/20 0.50
▸ GRIN1 Q05586 1/20 0.50
▸ GRIN2A Q12879 1/20 0.50
▸ GRIN2B Q13224 1/20 0.50
▸ GRIN2C Q14957 1/20 0.50
▸ GRIN3A Q8TCU5 1/20 0.50
▸ GLP1R P43220 2/20 0.50
▸ TFPI P10646 1/20 0.50
▸ BACE1 P56817 2/20 0.49
▸ BACE2 Q9Y5Z0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30752382 1.00 VIPR1 (0.53) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL29907889 1.00 VIPR1 (0.53) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL30752379 0.99 VIPR1 (0.55) VIPR1VIPR2KISS1RGLP1RBACE1
SCHEMBL31622476 0.99 VIPR1 (0.55) VIPR1VIPR2KISS1RGLP1RBACE1
SCHEMBL31622480 0.99 VIPR1 (0.52) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL30618090 0.99 VIPR1 (0.52) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL30752385 0.98 VIPR1 (0.52) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL30752387 0.98 VIPR1 (0.52) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL30712758 0.97 VIPR1 (0.50) VIPR1VIPR2KISS1RGRIN2DGRIN3B
SCHEMBL15669773 0.95 TFPI (0.53) VIPR1VIPR2KISS1RGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722236-A1 INSULIN DERIVATIVE AND USE THEREOF The United Bio-Technology (Hengqin) Co., Ltd. (CN) 2026-04-08 — — EP disclosed
EP-4623900-A2 METHODS AND COMPOSITIONS FOR THE PREVENTION OF TYPE 1 DIABETES Dr. Mary Morris & Associates, LLC (US) 2025-10-01 — — EP disclosed
US-12410228-B2 Insulin analogs UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-09-09 — — US disclosed
CN-119454911-A Compositions comprising long acting insulin analogue conjugates and long acting insulinotropic peptide conjugates for treating diabetes 韩美药品株式会社 2025-02-18 — — CN disclosed
WO-2024239961-A1 INSULIN DERIVATIVE AND USE THEREOF 联邦生物科技(珠海横琴)有限公司 2024-11-28 — — WO disclosed
CN-114989289-B Novel insulin analogues and uses thereof 韩美药品株式会社 2024-10-01 — — CN disclosed
CN-117487026-A insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2024-02-02 — — CN disclosed
CN-110339369-B Improved process for preparing physiologically active polypeptide complexes 韩美科学株式会社 2024-01-23 — — CN disclosed
CN-117337299-A Molecular design of glucose responsive insulin analogue glucose sensor 印地安纳大学理事会 2024-01-02 — — CN disclosed
CN-117242098-A Conformationally constrained glucagon analogs and their use in glucagon-single chain insulin fusion proteins 印地安纳大学理事会 2023-12-15 — — CN disclosed
EP-4230216-A1 INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF Jiangsu Gensciences Inc. (CN) 2023-08-23 — — EP disclosed
CN-110072884-B Insulin analogues 犹他大学研究基金会 2023-07-28 — — CN disclosed
US-20220340636-A1 INSULIN ANALOGS UNIVERSITY OF UTAH RESEARCH FOUNDATION 2022-10-27 — — US disclosed
US-20220288213-A1 INSULIN ANALOGUES WITH GLUCOSE REGULATED CONFORMATIONAL SWITCH THERMALIN INC (US) 2022-09-15 — — US disclosed
WO-2022125587-A9 ACYLATED SINGLE-CHAIN INSULIN ANALOGUES CASE WESTERN RESERVE UNIVERSITY (US) 2022-07-21 — — WO disclosed
WO-2022125587-A1 ACYLATED SINGLE-CHAIN INSULIN ANALOGUES CASE WESTERN RESERVE UNIVERSITY (US) 2022-06-16 — — WO disclosed
EP-4007594-A1 PREMIXED ULTRA-STABLE SINGLE-CHAIN INSULIN ANALOGUE FORMULATIONS CASE WESTERN RESERVE UNIVERSITY (US) 2022-06-08 — — EP disclosed
US-11248034-B2 Insulin analogs UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-02-15 — — US disclosed
WO-2022017309-A1 INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF 江苏晟斯生物制药有限公司 2022-01-27 — — WO disclosed
CN-113968911-A insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2022-01-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288213-A1 INSULIN ANALOGUES WITH GLUCOSE REGULATED CONFORMATIONAL SWITCH IAPP, GPR119, INSR VIPR1 328/4885VIPR2 434/4885KISS1R 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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