SCHEMBL29354566

SCHEMBL29354566

CC(C)(C)c1ccc(O)c(N=Cc2cccc([N+](=O)[O-])c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.53
CDK2 P24941 1/20 0.53
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
PTGS2 P35354 1/20 0.49
MAPT P10636 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 3/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 2/20 0.45
MAOB P27338 1/20 0.44
HTT P42858 2/20 0.44
PSMD14 O00487 1/20 0.44
LMNA P02545 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623371 1.00 GAA (0.53) GAACDK2MEN1KMT2APTGS2
SCHEMBL623370 1.00 GAA (0.53) GAACDK2MEN1KMT2APTGS2
SCHEMBL15315387 0.90 KMT2A (0.50) GAACDK2MEN1KMT2APTGS2
SCHEMBL18688530 0.89 KMT2A (0.49) GAACDK2MEN1KMT2APTGS2
SCHEMBL13479601 0.86 MAPT (0.47) GAACDK2MEN1KMT2AMAPT
SCHEMBL22624828 0.84 CDK2 (0.56) CDK2MEN1KMT2APTGS2MAPT
SCHEMBL10118539 0.81 MEN1 (0.60) CDK2MEN1KMT2APTGS2MAPT
SCHEMBL15312914 0.81 MEN1 (0.60) CDK2MEN1KMT2APTGS2MAPT
SCHEMBL15317953 0.80 MAPT (0.54) GAAMEN1KMT2APTGS2MAPT
SCHEMBL623631 0.79 GAA (0.63) GAACDK2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4215614-A1 COMBINATION THERAPY FOR DYSTROPHIN-RELATED DISEASES Dynacure (FR) 2023-07-26 EP claimed
US-20260132180-A1 ONCOSELECTIVE THERAPY KERNAL BIOLOGICS, INC. 2026-05-14 US disclosed
EP-4709864-A1 ONCOSELECTIVE THERAPY Kernal Biologics, Inc. (US) 2026-03-18 EP disclosed
EP-4634662-A1 POTENCY ASSAY FOR PHARMACEUTICAL PRODUCTS Repairon Muscle UG (haftungsbeschränkt) (DE) 2025-10-22 EP disclosed
WO-2024255817-A1 SYSTEMS AND METHOD OF INHIBITING NONSENSE-MEDIATED DECAY WITH CIRCULAR RNAS PEKING UNIVERSITY (CN) 2024-12-19 WO disclosed
WO-2024233835-A1 ONCOSELECTIVE THERAPY KERNAL BIOLOGICS, INC. (US) 2024-11-14 WO disclosed
CN-118922359-A Sorting system and sorting method 株式会社大福 2024-11-08 CN disclosed
US-20240358797-A1 ONCOSELECTIVE CANCER THERAPY KERNAL BIOLOGICS, INC. 2024-10-31 US disclosed
EP-4429645-A1 ONCOSELECTIVE CANCER THERAPY Kernal Biologics, Inc. (US) 2024-09-18 EP disclosed
WO-2024176694-A1 SORTING SYSTEM AND SORTING METHOD 株式会社ダイフク 2024-08-29 WO disclosed
WO-2023149370-A1 CONTROL SYSTEM, CONTROL METHOD, AND STORAGE MEDIUM キヤノン株式会社 2023-08-10 WO disclosed
EP-4215614-A1 COMBINATION THERAPY FOR DYSTROPHIN-RELATED DISEASES Dynacure (FR) 2023-07-26 EP disclosed
WO-2023081885-A1 ONCOSELECTIVE CANCER THERAPY KERNAL BIOLOGICS, INC. (US) 2023-05-11 WO disclosed
EP-3647957-B1 SUBSTRATE-RELATED OPERATION MACHINE CONTROL DEVICE FUJI CORP (JP) 2022-10-19 EP disclosed
WO-2022200857-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS MONTE ROSA THERAPEUTICS AG (CH) 2022-09-29 WO disclosed
CN-114729353-A Expression of engineered tumor-selective proteins 科纳勒生物公司 2022-07-08 CN disclosed
CN-111447028-B Time synchronization method and device 新华三信息安全技术有限公司 2022-05-24 CN disclosed
EP-3987028-A1 ENGINEERED ONCOSELECTIVE PROTEIN EXPRESSION Kernal Biologics, Inc. (US) 2022-04-27 EP disclosed
CN-114114887-A Control device and control method for electronic device, timepiece body, and band 卡西欧计算机株式会社 2022-03-01 CN disclosed
CN-109150955-B Communication apparatus, communication method, and recording medium 卡西欧计算机株式会社 2022-01-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132180-A1 ONCOSELECTIVE THERAPY TRMT1L, NTPCR, DCTD GAA 3040/4885CDK2 3994/4885MEN1 1665/4885
US-20240358797-A1 ONCOSELECTIVE CANCER THERAPY CD274, PDCD1LG2, PDCD1 GAA 931/4885CDK2 3524/4885MEN1 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.