Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373545 | 1.00 | GAA (0.63) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL623630 | 1.00 | GAA (0.63) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL15317953 | 0.85 | MAPT (0.54) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL22103729 | 0.85 | GAA (0.72) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL15315387 | 0.81 | KMT2A (0.50) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL18688530 | 0.80 | KMT2A (0.49) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL29354566 | 0.79 | GAA (0.53) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL623370 | 0.79 | GAA (0.53) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL623371 | 0.79 | GAA (0.53) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL14337265 | 0.79 | PTGS2 (0.47) | GAAMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274283-A1 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-17 | — | — | US | claimed |
| WO-2012021707-A2 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-16 | — | — | WO | claimed |
| EP-3638647-B1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| CN-110740987-B | Method for mono-N-alkylation of aminophenols | SABIC环球技术有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| US-11066354-B2 | Process for mono N-alkylation of aminophenol | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-07-20 | — | — | US | disclosed |
| US-20200140373-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-05-07 | — | — | US | disclosed |
| EP-3638647-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC Global Technologies B.V. (NL) | 2020-04-22 | — | — | EP | disclosed |
| CN-110740987-A | Process for mono-N-alkylation of aminophenols | SABIC环球技术有限责任公司 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018228981-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274283-A1 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | UPF1, NUDT21, RNGTT | GAA 2293/4885MEN1 3033/4885KMT2A 1956/4885 |
| US-11066354-B2 | Process for mono N-alkylation of aminophenol | CYP4A11, CYP4B1, TYR | GAA 2261/4885MEN1 2612/4885KMT2A 1118/4885 |
| US-20200140373-A1 | PROCESS FOR MONO N-ALKYLATION OF AMINOPHENOL | CYP4A11, CYP4B1, TYR | GAA 2261/4885MEN1 2612/4885KMT2A 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.