Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026368 | 0.84 | NPSR1 (0.48) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL4210468 | 0.83 | NPSR1 (0.46) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL28427246 | 0.81 | NPSR1 (0.48) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL11264516 | 0.81 | POLB (0.49) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL27959135 | 0.81 | L3MBTL1 (0.46) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL11245673 | 0.78 | NPSR1 (0.42) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL10351899 | 0.77 | ALDH1A1 (0.41) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| Acetic Acid SCHEMBL27814143 | 0.77 | NPSR1 (0.41) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL27734421 | 0.77 | MEN1 (0.56) | NPSR1ATMKMT2AALDH1A1POLB | |
| SCHEMBL4654046 | 0.76 | NPSR1 (0.43) | NPSR1ATMTDP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229391-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077766-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |
| EP-0008177-B1 | VULCANIZABLE RUBBER COMPOSITIONS CONTAINING SUBSTITUTED CARBAMIC ACID ESTERS | MONSANTO COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0008177-A1 | Vulcanizable rubber compositions containing substituted carbamic acid esters | MONSANTO COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4156680-A | Scorch inhibited vulcanizable rubber compositions containing carbamic acid esters | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |