SCHEMBL293550

SCHEMBL293550

CC(C)(O)c1cc(-c2cccc3ccccc23)c(C(C)(C)O)cc1-c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.41
PPARA Q07869 3/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PPARD Q03181 1/20 0.41
SLC22A12 Q96S37 1/20 0.40
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
KDM4E B2RXH2 3/20 0.39
ALPL P05186 1/20 0.39
GAA P10253 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ALOX5 P09917 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
MCL1 Q07820 1/20 0.37
ACMSD Q8TDX5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10299008 0.92 PPARG (0.46) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL1559816 0.91 ALDH1A1 (0.45) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL1559755 0.88 CYP1A2 (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL10010552 0.87 PPARG (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL16219736 0.84 AKR1C3 (0.37) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL17836992 0.84 KCNJ11 (0.38) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL17070748 0.83 CA12 (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL9270026 0.81 DHFR (0.42) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL17061422 0.81 PPARG (0.38) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL291785 0.80 CYP2D6 (0.40) PPARGPPARACYP2C9CYP2C19PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
EP-2024310-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-14 EP disclosed
EP-2024310-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-14 EP disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
EP-2024310-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2009-02-18 EP disclosed
WO-2007140847-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-12-13 WO disclosed
WO-2007140847-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2A1, SLCO1A2 PPARG 3585/4885PPARA 4249/4885CYP2C9 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.