Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940292 | 0.84 | CHRNB4 (0.55) | CHRNB4CHRNA3ROCK2ROCK1CDC42BPB | |
| SCHEMBL2935652 | 0.84 | CHRNB4 (0.43) | CHRNB4CHRNA3ROCK2ROCK1CDC42BPB | |
| SCHEMBL2938484 | 0.83 | MAP2K7 (0.42) | CHRNB4CHRNA3CHRNB2CHRNA4FFAR1 | |
| SCHEMBL2932236 | 0.79 | FPR1 (0.45) | FPR1FPR2HDAC8HDAC6HDAC1 | |
| SCHEMBL4081189 | 0.78 | MAP2K7 (0.39) | CHRNB4CHRNA3FFAR1 | |
| SCHEMBL2941517 | 0.76 | ROCK2 (0.42) | CHRNB4CHRNA3ROCK2ROCK1CDC42BPB | |
| SCHEMBL2937114 | 0.76 | HSD17B10 (0.38) | — | |
| SCHEMBL5037356 | 0.75 | ADORA2A (0.41) | CHRNB4CHRNA3ROCK2ROCK1CDC42BPB | |
| SCHEMBL5037350 | 0.75 | ADORA2A (0.41) | CHRNB4CHRNA3ROCK2ROCK1CDC42BPB | |
| SCHEMBL2939993 | 0.75 | FPR1 (0.46) | FPR1FPR2HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | claimed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | disclosed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1752192-A1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | Wella Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033745-A1 | Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene | TACR1, KRT18, AKR1C4 | CHRNB4 979/4885CHRNA3 1452/4885ROCK2 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.