SCHEMBL29355159

SCHEMBL29355159

Cc1nnc(C#N)c(-c2c(F)cccc2F)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 2/20 0.41
FLT1 P17948 2/20 0.41
KDR P35968 2/20 0.41
GSK3A P49840 2/20 0.41
GSK3B P49841 2/20 0.41
LIMK1 P53667 2/20 0.41
DYRK1A Q13627 2/20 0.41
ABL1 P00519 1/20 0.41
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
GRK5 P34947 1/20 0.41
MAP2K2 P36507 1/20 0.41
CDK8 P49336 1/20 0.41
PRKX P51817 1/20 0.41
NEK2 P51955 1/20 0.41
MAP2K1 Q02750 1/20 0.41
PRKCQ Q04759 1/20 0.41
MAP4K2 Q12851 1/20 0.41
IKBKE Q14164 1/20 0.41
NTRK3 Q16288 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015938 1.00 CHEK1 (0.41) CHEK1FLT1KDRGSK3AGSK3B
SCHEMBL10015880 0.89 CHEK1 (0.39) CHEK1FLT1KDRGSK3AGSK3B
SCHEMBL10015955 0.84 MAOB (0.47) CHEK1MAOBALDH1A1CYP1A2CYP2C9
SCHEMBL3309386 0.81 GAA (0.38) HTTKDM4EALDH1A1CYP1A2CYP2C9
SCHEMBL3311654 0.81 PTGES (0.39) HTTRXFP1KDM4EALDH1A1CYP2C9
SCHEMBL3311645 0.77 ERBB2 (0.37) HSD17B10KDM4EALDH1A1ERBB2HPGD
SCHEMBL14962992 0.77 CYP1A2 (0.42) CHEK1MAOBALDH1A1CYP1A2CYP2C9
SCHEMBL10015953 0.77 MAOB (0.42) CHEK1MAOBHTTKDM4EALDH1A1
SCHEMBL3303729 0.75 AR (0.36) HSD17B10HTTRXFP1KDM4EALDH1A1
SCHEMBL2872817 0.73 MAOB (0.60) CHEK1CDK8MAOBHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118368985-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-19 CN claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
EP-4747241-A1 BENZIMIDAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-05-27 EP disclosed
WO-2026047037-A1 MICROBIOCIDAL QUINOLINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-03-05 WO disclosed
EP-4695246-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695252-A1 IMIDAZO[1,2-A]PYRAZINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695253-A1 IMIDAZO BICYCLIC DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695251-A1 IMIDAZO[1,2-A]PYRAZINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695245-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4694686-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
WO-2022043576-A2 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-03-03 WO disclosed
CN-114072384-A Microbicidal picolinamide derivatives 先正达农作物保护股份公司 2022-02-18 CN disclosed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
EP-3947371-A1 MICROBIOCIDAL THIAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2022-02-09 EP disclosed
WO-2022026229-A1 FORMULATIONS SYNGENTA CROP PROTECTION AG (CH) 2022-02-03 WO disclosed
CN-113979962-A Fungicidal compositions 先正达参股股份有限公司 2022-01-28 CN disclosed
WO-2022017975-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-01-27 WO disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 EP disclosed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN disclosed