Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178281 | 1.00 | TLR4 (0.31) | TLR4 | |
| SCHEMBL25693758 | 0.97 | TLR4 (0.30) | TLR4 | |
| SCHEMBL8967180 | 0.96 | NPC1 (0.32) | — | |
| SCHEMBL25693749 | 0.96 | — | — | |
| SCHEMBL25693752 | 0.95 | — | — | |
| SCHEMBL18134233 | 0.95 | TLR4 (0.31) | TLR4 | |
| SCHEMBL8967196 | 0.93 | — | — | |
| SCHEMBL25693760 | 0.93 | — | — | |
| SCHEMBL25693761 | 0.93 | — | — | |
| SCHEMBL25693743 | 0.93 | HTR2C (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183572-A1 | LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20230167362-A1 | NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-1852429-B1 | Hexahydro dibenzofuran derivatives | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| US-7417157-B2 | Hexahydrodibenzofuran derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1852429-A1 | Hexahydro dibenzofuran derivatives | Merck Patent GmbH (DE) | 2007-11-07 | — | — | EP | disclosed |
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | MERCK PATENT GMBH | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070247585-A1 | Hexahydrodibenzofuran derivatives | HEXD, CFD, EDF1 | TLR4 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.