Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667173 | 1.00 | MAPT (0.44) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL17080158 | 0.91 | MAPT (0.42) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL17080280 | 0.90 | ALDH1A1 (0.44) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL18667171 | 0.88 | MAPT (0.42) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL21250354 | 0.88 | ALDH1A1 (0.45) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL21250422 | 0.88 | MAPT (0.44) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL18667460 | 0.88 | MAPT (0.41) | MAPTPOLBALDH1A1PKMHPGD | |
| Vebicorvir SCHEMBL21250344 | 0.87 | MAPT (0.40) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL18667100 | 0.87 | ALDH1A1 (0.42) | MAPTPOLBALDH1A1PKMHPGD | |
| SCHEMBL18667099 | 0.87 | ALDH1A1 (0.42) | MAPTPOLBALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025890-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2024-01-25 | — | — | US | disclosed |
| US-11814376-B2 | Hepatitis b core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230044112-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-02-09 | — | — | US | disclosed |
| US-20220023311-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025890-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | MAPT 2896/4885POLB 1965/4885ALDH1A1 4316/4885 |
| US-20230044112-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | MAPT 2896/4885POLB 1965/4885ALDH1A1 4316/4885 |
| US-11814376-B2 | Hepatitis b core protein modulators | HAVCR2, FABP1, MAVS | MAPT 2896/4885POLB 1965/4885ALDH1A1 4316/4885 |
| US-20220023311-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | MAPT 3090/4885POLB 1770/4885ALDH1A1 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.