SCHEMBL29358409

SCHEMBL29358409

O=Cc1c(O)ccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 1.00
KDM4E B2RXH2 6/20 0.60
HTT P42858 2/20 0.60
NPC1 O15118 1/20 0.60
MAPT P10636 8/20 0.56
KMT2A Q03164 5/20 0.56
L3MBTL1 Q9Y468 5/20 0.54
MEN1 O00255 4/20 0.54
GAA P10253 3/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
ATM Q13315 1/20 0.54
RRM1 P23921 1/20 0.54
PTPN22 Q9Y2R2 1/20 0.54
THRB P10828 3/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
MPI P34949 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CRHBP P24387 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304032 1.00 ERN1 (1.00) ERN1KDM4EHTTNPC1MAPT
SCHEMBL11520332 0.98 ERN1 (0.96) ERN1KDM4EHTTNPC1MAPT
SCHEMBL11407376 0.98 ERN1 (0.96) ERN1KDM4EHTTNPC1MAPT
Hydrazine SCHEMBL28732767 0.96 ERN1 (0.92) ERN1KDM4EHTTNPC1MAPT
Phenol SCHEMBL2787265 0.93 ERN1 (0.86) ERN1KDM4EHTTNPC1MAPT
SCHEMBL10615396 0.90 ERN1 (0.82) ERN1KDM4EHTTNPC1MAPT
Orthocresol SCHEMBL2131451 0.88 ERN1 (0.77) ERN1KDM4EHTTNPC1MAPT
SCHEMBL5823063 0.85 KDM4E (0.73) ERN1KDM4EHTTNPC1MAPT
SCHEMBL249731 0.83 ERN1 (0.71) ERN1KDM4EHTTNPC1MAPT
SCHEMBL7915285 0.83 ERN1 (0.70) ERN1KDM4EHTTNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069594-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS INST NAT SANTE RECH MED (FR) 2026-03-12 US claimed
EP-4580611-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP claimed
EP-4534266-A1 CHEMICAL MODIFICATION OF WOOD TO IMPROVE LIGHT FASTNESS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2025-04-09 EP claimed
WO-2024047196-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS Institut National de la Santé et de la Recherche Médicale (FR) 2024-03-07 WO claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20220184083-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-06-16 US claimed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP claimed
EP-3941448-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2022-01-26 EP claimed
US-20260069594-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS INST NAT SANTE RECH MED (FR) 2026-03-12 US disclosed
EP-4580611-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP disclosed
EP-4534266-A1 CHEMICAL MODIFICATION OF WOOD TO IMPROVE LIGHT FASTNESS Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2025-04-09 EP disclosed
CN-112955141-B Improved method for inducing tissue regeneration and senescent cell lysis in mammalian cells AGEX治疗公司 2025-02-14 CN disclosed
EP-4423055-A1 SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES Consejo Superior de Investigaciones Cientificas (ES) 2024-09-04 EP disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 US disclosed
US-20220184083-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-06-16 US disclosed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP disclosed
WO-2022104222-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME SWIMC LLC (US) 2022-05-19 WO disclosed
CN-114456279-A Preparation method of chitosan hydroxy naphthalene aldehyde Schiff base and chitosan hydroxy naphthalene aldehyde Schiff base copper complex, and product and application thereof 西南林业大学 2022-05-10 CN disclosed
WO-2022070946-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, DISPLAY DEVICE, AND METHOD FOR PRODUCING CURED PRODUCT 東レ株式会社 2022-04-07 WO disclosed
WO-2022043496-A2 USE OF MAIT CELLS AS BIOMARKERS AND BIOTARGETS IN COVID-19 INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ERN1 4459/4885KDM4E 1526/4885HTT 791/4885
US-20260069594-A1 USE OF AN AGENT CAPABLE OF INHIBITING THE ACTIVATION OF MAIT CELLS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS MIF, MTX1, PTGS1 ERN1 4655/4885KDM4E 2194/4885HTT 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.