Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 7/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356769 | 0.91 | GPR52 (0.40) | GPR52GRM2RPS6KB1CYP11B1CYP11B2 | |
| SCHEMBL29355483 | 0.89 | GPR52 (0.42) | GPR52GRM2CASP1TGFBR1TGFBR2 | |
| SCHEMBL29353790 | 0.87 | TSHR (0.40) | GPR52GRM2CYP11B1CYP11B2 | |
| SCHEMBL29355501 | 0.87 | GPR52 (0.41) | GPR52RPS6KB1CYP11B1CYP11B2 | |
| SCHEMBL29356944 | 0.85 | GPR52 (0.37) | GPR52GRM2RPS6KB1CYP11B1CYP11B2 | |
| SCHEMBL29356172 | 0.85 | CYP11B1 (0.36) | GRM2TGFBR1TGFBR2RPS6KB1CYP11B1 | |
| SCHEMBL29356847 | 0.85 | GPR52 (0.41) | GPR52RPS6KB1CYP11B1CYP11B2 | |
| SCHEMBL29356208 | 0.82 | CDK8 (0.41) | CASP1TGFBR1TGFBR2RPS6KB1 | |
| SCHEMBL29353808 | 0.82 | GPR52 (0.44) | GPR52CASP1RPS6KB1CYP11B1CYP11B2 | |
| SCHEMBL29357135 | 0.80 | GPR52 (0.44) | GPR52GRM2RPS6KB1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |