Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356944 | 0.91 | GPR52 (0.37) | CYP11B1CYP11B2GRM2RPS6KB1 | |
| SCHEMBL29353790 | 0.89 | TSHR (0.40) | CYP11B1CYP11B2GRM2KDM4E | |
| SCHEMBL29356847 | 0.88 | GPR52 (0.41) | CYP11B1CYP11B2RPS6KB1AKT1JAK3 | |
| SCHEMBL29356769 | 0.88 | GPR52 (0.40) | CYP11B1CYP11B2GRM2FYNRPS6KB1 | |
| SCHEMBL29358585 | 0.85 | GPR52 (0.42) | CYP11B1CYP11B2GRM2RPS6KB1TGFBR1 | |
| SCHEMBL29357135 | 0.85 | GPR52 (0.44) | CYP11B1CYP11B2GRM2RPS6KB1 | |
| SCHEMBL29353893 | 0.84 | GPR52 (0.44) | CYP11B1CYP11B2GRM2 | |
| SCHEMBL29355501 | 0.82 | GPR52 (0.41) | CYP11B1CYP11B2RPS6KB1AKT1JAK3 | |
| SCHEMBL29357168 | 0.80 | CYP11B2 (0.34) | CYP11B1CYP11B2GRM2KCNH2 | |
| SCHEMBL29355532 | 0.79 | IDH1 (0.41) | CYP11B1CYP11B2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |