SCHEMBL29359744

SCHEMBL29359744

O=C(NC1CCCc2ccccc21)c1ncccc1C1CCNCC1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
TSHR P16473 2/20 0.57
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
HTT P42858 1/20 0.56
TAS1R3 Q7RTX0 4/20 0.55
TAS1R1 Q7RTX1 4/20 0.55
TAS1R2 Q8TE23 4/20 0.55
P2RX7 Q99572 1/20 0.53
LMNA P02545 2/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP2D6 P10635 1/20 0.51
CNR1 P21554 2/20 0.49
CNR2 P34972 2/20 0.49
RECQL P46063 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3392204 0.79 HTT (0.61) ALDH1A1TSHRNPC1RAB9AHTT
SCHEMBL3391272 0.79 HTT (0.61) ALDH1A1TSHRNPC1RAB9AHTT
SCHEMBL29563786 0.77 HTT (0.65) ALDH1A1TSHRHTTTAS1R3TAS1R1
SCHEMBL4064260 0.75 ALDH1A1 (0.57) ALDH1A1TSHRNPC1RAB9AHTT
SCHEMBL29694265 0.75 HTT (0.53) ALDH1A1TSHRNPC1RAB9AHTT
SCHEMBL12505792 0.73 HTT (0.80) ALDH1A1TSHRHTTTAS1R3TAS1R1
SCHEMBL2406255 0.73 HTT (1.00) ALDH1A1TSHRHTTTAS1R3TAS1R1
SCHEMBL5436807 0.73 HTT (1.00) ALDH1A1TSHRHTTTAS1R3TAS1R1
SCHEMBL14082169 0.72 HTT (0.71) ALDH1A1TSHRHTTTAS1R3TAS1R1
SCHEMBL19554094 0.72 KDM4E (0.56) ALDH1A1TSHRNPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022090069-A1 COMPOSITIONS COMPRISING MEFENPYR-DIETHYL BASF SE (DE) 2022-05-05 WO disclosed
WO-2022090071-A1 USE OF MEFENPYR-DIETHYL FOR CONTROLLING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2022-05-05 WO disclosed
WO-2022017836-A1 FUNGICIDAL COMPOSITIONS COMPRISING (R)-2-[4-(4-CHLOROPHENOXY)-2-(TRIFLUOROMETHYL)PHENYL]-1- (1,2,4-TRIAZOL-1-YL)PROPAN-2-OL BASF Agro B.V. (NL) 2022-01-27 WO disclosed