Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.74 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.74 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | DHODH | Q02127 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436807 | 1.00 | HTT (1.00) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL22289415 | 0.92 | HTT (0.84) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL30823638 | 0.92 | HTT (0.84) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL3459886 | 0.91 | HTT (0.83) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL3460628 | 0.91 | HTT (0.83) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL2465110 | 0.91 | HTT (0.83) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL29742388 | 0.91 | HTT (0.83) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL6572555 | 0.90 | LMNA (0.82) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL21780113 | 0.90 | HTT (0.82) | HTTLMNAKMT2AALDH1A1TAS1R3 | |
| SCHEMBL11272127 | 0.89 | HTT (0.80) | HTTLMNAKMT2AALDH1A1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8389720-B2 | Quinolone neuropeptide S receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20110212946-A1 | Quinolone Neuropeptide S Receptor Antagonists | MERCK SHARP & DOHME LLC | 2011-09-01 | — | — | US | disclosed |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | HTT 4100/4885LMNA 4766/4885KMT2A 581/4885 |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | HTT 4100/4885LMNA 4766/4885KMT2A 581/4885 |
| US-20110212946-A1 | Quinolone Neuropeptide S Receptor Antagonists | NPSR1, NPY1R, NPY2R | HTT 408/4885LMNA 3299/4885KMT2A 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.