Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.82 |
| ▸ | RELA | Q04206 | 2/20 | 0.82 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MYLK | Q15746 | 1/20 | 0.37 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359598 | 1.00 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ELANE | |
| Altersolanol A SCHEMBL29845341 | 0.90 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ELANE | |
| Altersolanol A SCHEMBL14923292 | 0.90 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ELANE | |
| Altersolanol A SCHEMBL8734898 | 0.90 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ELANE | |
| Altersolanol A SCHEMBL29688970 | 0.90 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ELANE | |
| Altersolanol A SCHEMBL2793105 | 0.90 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ELANE | |
| SCHEMBL8735134 | 0.85 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ELANE | |
| SCHEMBL8736848 | 0.85 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ELANE | |
| SCHEMBL6114092 | 0.81 | NFKB1 (0.74) | NFKB1NFKB2RELAIDO1ELANE | |
| SCHEMBL3785760 | 0.81 | NFKB1 (0.74) | NFKB1NFKB2RELAIDO1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |