Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MYLK | Q15746 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Altersolanol A SCHEMBL2793105 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| Altersolanol A SCHEMBL29688970 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| Altersolanol A SCHEMBL14923292 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| Altersolanol A SCHEMBL29845341 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL8735134 | 0.90 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL8736848 | 0.90 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL29359598 | 0.90 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL29360149 | 0.90 | NFKB1 (0.82) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL6114092 | 0.85 | NFKB1 (0.74) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL3785760 | 0.85 | NFKB1 (0.74) | NFKB1NFKB2RELAIDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435394-B1 | NOVEL ANTHRAQUINONE DERIVATIVES | SEALIFE PHARMA GMBH (AT) | 2013-05-08 | — | — | EP | disclosed |
| US-20120129927-A1 | New Anthraquinone Derivatives | SEALIFE PHARMA GMBH (AT) | 2012-05-24 | — | — | US | disclosed |
| US-20120129927-A1 | New Anthraquinone Derivatives | SEALIFE PHARMA GMBH (AT) | 2012-05-24 | — | — | US | disclosed |
| WO-2010135759-A1 | NOVEL ANTHRAQUINONE DERIVATIVES | SEALIFE PHARMA GMBH (AT) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129927-A1 | New Anthraquinone Derivatives | ANXA1, ANTXR2, ANXA11 | NFKB1 1413/4885NFKB2 1824/4885RELA 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.