Sumatriptan

Sumatriptan

SCHEMBL29360288

CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1.O=C(O)CCC(=O)O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

HTR1BHTR1D

The experimentally established mechanism targets of Sumatriptan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR1D known ✓ P28221 9/20 0.85
HTR1B known ✓ P28222 8/20 0.85
HTR1A P08908 10/20 0.85
HTR2A P28223 4/20 0.85
HTR2C P28335 3/20 0.85
HTR7 P34969 2/20 0.85
HTR5A P47898 2/20 0.85
HTR2B P41595 2/20 0.85
HTR1E P28566 1/20 0.85
HTR1F P30939 1/20 0.85
HTR3A P46098 1/20 0.85
SLC47A1 Q96FL8 1/20 0.85
HTR6 P50406 1/20 0.58
LMNA P02545 1/20 0.58
ADRA2B P18089 1/20 0.58
KCNH2 Q12809 1/20 0.58
KMT2A Q03164 1/20 0.52
SLC6A4 P31645 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sumatriptan SCHEMBL2404748 1.00 HTR1A (0.85) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL2405528 1.00 HTR1A (0.85) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL41674 1.00 HTR1A (0.85) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL1556482 1.00 HTR1A (0.85) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL27887904 0.99 HTR1A (0.84) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL4132936 0.99 HTR1A (0.84) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL6684827 0.99 HTR1A (0.84) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL6688024 0.97 HTR1A (0.80) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL4308781 0.97 HTR1A (0.80) HTR1AHTR1DHTR1BHTR2AHTR2C
Sumatriptan SCHEMBL4311406 0.97 HTR1A (0.80) HTR1AHTR1DHTR1BHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
US-12257371-B2 SiOx barrier for pharmaceutical package and coating process SIO2 MEDICAL PRODUCTS, LLC (US) 2025-03-25 US claimed
US-20240074944-A1 PECVD COATED PHARMACEUTICAL PACKAGING OAKTREE FUND ADMINISTRATION, LLC 2024-03-07 US claimed
CN-117241773-A Polymer medicine bottle with standard external dimensions and reduced internal volume SIO2医疗产品有限公司 2023-12-15 CN claimed
US-20230303305-A1 METHOD AND PACKAGE FOR REDUCING THE DEGRADATION OF A DRUG AND/OR EXCIPIENT, E.G. POLYSORBATE STABILIZER, IN A PHARMACEUTICAL PRODUCT OAKTREE FUND ADMINISTRATION, LLC 2023-09-28 US claimed
EP-4247316-A1 POLYMER VIALS HAVING STANDARD EXTERNAL DIMENSIONS AND REDUCED INTERNAL VOLUME SiO2 Medical Products, Inc. (US) 2023-09-27 EP claimed
CN-116782865-A Atomic layer deposition coated pharmaceutical packages, improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines SIO2医药产品公司 2023-09-19 CN claimed
US-20230277415-A1 POLYMER VIALS HAVING STANDARD EXTERNAL DIMENSIONS AND REDUCED INTERNAL VOLUME SIO2 MEDICAL PRODUCTS, INC. 2023-09-07 US claimed
US-20230263957-A1 ATOMIC LAYER DEPOSITION COATED PHARMACEUTICAL PACKAGING AND IMPROVED SYRINGES AND VIALS, E.G. FOR LYOPHILIZED/COLD-CHAIN DRUGS/VACCINES OAKTREE FUND ADMINISTRATION, LLC 2023-08-24 US claimed
US-11724860-B2 Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus SIO2 MEDICAL PRODUCTS, INC. (US) 2023-08-15 US claimed
US-11684546-B2 PECVD coated pharmaceutical packaging SIO2 MEDICAL PRODUCTS, INC. (US) 2023-06-27 US claimed
EP-4188996-A1 METHOD AND PACKAGE FOR REDUCING THE DEGRADATION OF A DRUG AND/OR EXCIPIENT, E.G. POLYSORBATE STABILIZER, IN A PHARMACEUTICAL PRODUCT SiO2 Medical Products, Inc. (US) 2023-06-07 EP claimed
EP-4168068-A1 ATOMIC LAYER DEPOSITION COATED PHARMACEUTICAL PACKAGING AND IMPROVED SYRINGES AND VIALS, E.G. FOR LYOPHILIZED/COLD-CHAIN DRUGS/VACCINES SiO2 Medical Products, Inc. (US) 2023-04-26 EP claimed
US-20220244247-A1 PECVD COATED PHARMACEUTICAL PACKAGING OAKTREE FUND ADMINISTRATION, LLC 2022-08-04 US claimed
WO-2022109619-A1 POLYMER VIALS HAVING STANDARD EXTERNAL DIMENSIONS AND REDUCED INTERNAL VOLUME SIO2 MEDICAL PRODUCTS, INC. (US) 2022-05-27 WO claimed
US-20220161969-A1 PASSIVATION, pH PROTECTIVE OR LUBRICITY COATING FOR PHARMACEUTICAL PACKAGE, COATING PROCESS AND APPARATUS OAKTREE FUND ADMINISTRATION, LLC 2022-05-26 US claimed
US-11298293-B2 PECVD coated pharmaceutical packaging SIO2 MEDICAL PRODUCTS, INC. (US) 2022-04-12 US claimed
US-20260139378-A1 PULSED PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION PROCESS, SYSTEM, AND COATED VESSELS SIO2 MEDICAL PRODUCTS INC (US) 2026-05-21 US disclosed
WO-2022020512-A1 BAG FOR EASY DRAINAGE AND MANIPULATION W. L. GORE & ASSOCIATES, INC. (US) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139378-A1 PULSED PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION PROCESS, SYSTEM, AND COATED VESSELS VEGFA, FLT4, FLT1 HTR1D 1747/4885HTR1B 2409/4885HTR1A 2362/4885
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME MEN1, MYO1G, IL2 HTR1D 1884/4885HTR1B 1797/4885HTR1A 2363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.