Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 4/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615232 | 0.78 | NOTUM (0.69) | HSD17B3NOTUMKDM4EMAPT | |
| SCHEMBL29359963 | 0.77 | NOTUM (0.59) | HSD17B3NOTUMMEN1KMT2A | |
| SCHEMBL7416330 | 0.75 | NOTUM (0.62) | HSD17B3NOTUMPDK1PDK2PDK3 | |
| SCHEMBL29360258 | 0.70 | DRD2 (0.46) | — | |
| SCHEMBL2061420 | 0.69 | HSD17B3 (0.49) | HSD17B3NOTUMATAD2KDM4EMEN1 | |
| SCHEMBL7416927 | 0.69 | NOTUM (0.62) | HSD17B3NOTUMKDM4EMEN1MAPT | |
| SCHEMBL4798305 | 0.69 | HSD17B3 (1.00) | HSD17B3NOTUM | |
| SCHEMBL399536 | 0.68 | NOTUM (0.67) | HSD17B3NOTUMATAD2BRD4KDM4E | |
| SCHEMBL30340506 | 0.68 | NOTUM (0.67) | HSD17B3NOTUMATAD2BRD4KDM4E | |
| SCHEMBL7749897 | 0.68 | ADRB2 (0.54) | HSD17B3NOTUMPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022016690-A1 | LUCIFERASE SUBSTRATES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2022-01-27 | — | — | WO | disclosed |