Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522427 | 0.92 | SOS1 (0.39) | NFKB1NFKB2RELAIDO1SOS1 | |
| SCHEMBL23522410 | 0.86 | NFKB1 (0.45) | NFKB1NFKB2RELAIDO1PARP1 | |
| SCHEMBL23199091 | 0.79 | SOS1 (0.43) | NFKB1NFKB2RELAIDO1SOS1 | |
| SCHEMBL23522423 | 0.77 | IDO1 (0.46) | IDO1SOS1PTPN1 | |
| SCHEMBL23522371 | 0.77 | NFKB1 (0.50) | NFKB1NFKB2RELAIDO1PARP1 | |
| Alterporriol P SCHEMBL29360385 | 0.76 | NFKB1 (0.49) | NFKB1NFKB2RELAIDO1PARP1 | |
| Altersolanol B SCHEMBL30514811 | 0.74 | NFKB1 (0.52) | NFKB1NFKB2RELAIDO1SOS1 | |
| Altersolanol B SCHEMBL23522406 | 0.74 | NFKB1 (0.52) | NFKB1NFKB2RELAIDO1SOS1 | |
| Altersolanol C SCHEMBL23199105 | 0.73 | NFKB1 (0.66) | NFKB1NFKB2RELAIDO1 | |
| SCHEMBL23522388 | 0.70 | NFKB1 (0.41) | NFKB1NFKB2RELAIDO1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |