Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522371 | 0.92 | NFKB1 (0.50) | NFKB1NFKB2RELAELANEIDO1 | |
| Alterporriol C SCHEMBL29359613 | 0.85 | NFKB1 (0.70) | NFKB1NFKB2RELAELANEIDO1 | |
| Altersolanol C SCHEMBL23199105 | 0.85 | NFKB1 (0.66) | NFKB1NFKB2RELAELANEIDO1 | |
| SCHEMBL23522390 | 0.78 | ELANE (0.41) | NFKB1NFKB2RELAELANEIDO1 | |
| Alterporriol Q SCHEMBL29356749 | 0.77 | ELANE (0.56) | ELANEIDO1ALDH1A1KDM4EGLA | |
| Alterporriol Q SCHEMBL23522419 | 0.77 | ELANE (0.56) | ELANEIDO1ALDH1A1KDM4EGLA | |
| SCHEMBL29359665 | 0.76 | NFKB1 (0.55) | NFKB1NFKB2RELAELANEKDM4E | |
| SCHEMBL29360532 | 0.76 | NFKB1 (0.39) | NFKB1NFKB2RELAIDO1PARP1 | |
| SCHEMBL23522410 | 0.75 | NFKB1 (0.45) | NFKB1NFKB2RELAIDO1ALDH1A1 | |
| SCHEMBL23522375 | 0.74 | ELANE (0.70) | NFKB1NFKB2RELAELANEIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |