SCHEMBL29360570

SCHEMBL29360570

CC(C)(C)OC(=O)c1ccc(-n2[nH]cc(-n3ccnn3)c2=O)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 11/20 1.00
EGLN1 Q9GZT9 7/20 1.00
HIF1AN Q9NWT6 2/20 1.00
TET2 Q6N021 1/20 1.00
OGFOD1 Q8N543 1/20 1.00
TET1 Q8NFU7 1/20 1.00
P4HTM Q9NXG6 4/20 0.44
EGLN3 Q9H6Z9 1/20 0.43
CRBN Q96SW2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3703019 1.00 EGLN2 (1.00) EGLN2EGLN1HIF1ANTET2OGFOD1
Hydrochloric Acid SCHEMBL3703018 0.99 EGLN2 (0.98) EGLN2EGLN1HIF1ANTET2OGFOD1
SCHEMBL14980827 0.92 EGLN2 (0.85) EGLN2EGLN1HIF1ANTET2OGFOD1
SCHEMBL2572105 0.86 EGLN2 (0.75) EGLN2EGLN1HIF1ANTET2OGFOD1
Hydrochloric Acid SCHEMBL2569325 0.85 EGLN2 (0.74) EGLN2EGLN1HIF1ANTET2OGFOD1
Hydrochloric Acid SCHEMBL2570664 0.85 EGLN2 (0.74) EGLN2EGLN1HIF1ANTET2OGFOD1
SCHEMBL2570669 0.84 EGLN2 (0.72) EGLN2EGLN1HIF1ANTET2OGFOD1
Hydrochloric Acid SCHEMBL3706626 0.83 EGLN2 (0.71) EGLN2EGLN1HIF1ANTET2OGFOD1
SCHEMBL3706371 0.82 EGLN2 (0.69) EGLN2EGLN1HIF1ANTET2OGFOD1
SCHEMBL4752104 0.81 EGLN2 (0.68) EGLN2EGLN1HIF1ANTET2OGFOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119876014-A Anti-inflammatory mesenchymal stem cells and preparation method and application thereof 杨业国 2025-04-25 CN claimed
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 US claimed
CN-119365486-A EPO receptor agonists and antagonists 免疫先锋股份有限公司 2025-01-24 CN claimed
EP-4490187-A2 EPO RECEPTOR AGONISTS AND ANTAGONISTS Immunedge, Inc. (US) 2025-01-15 EP claimed
CN-117778303-A Application of IOX4 in promoting anti-inflammatory activity of human umbilical mesenchymal stem cells 恒峰铭成生物科技(上海)有限公司 2024-03-29 CN claimed
CN-117778302-A Application of IOX4 in treating umbilical mesenchymal exosomes and in delaying cell aging 恒峰铭成生物科技(上海)有限公司 2024-03-29 CN claimed
CN-117757734-A Application of IOX4 in resisting human umbilical cord mesenchymal stem cell aging 恒峰铭成生物科技(上海)有限公司 2024-03-26 CN claimed
WO-2023172989-A2 EPO RECEPTOR AGONISTS AND ANTAGONISTS IMMUNEDGE, INC. (US) 2023-09-14 WO claimed
US-20230201359-A1 MONOCYTE-SPECIFIC APTAMERS AND USES THEREOF FOR DELIVERING THERAPEUTIC AGENTS TO HEART ACADEMIA SINICA (TW) 2023-06-29 US claimed
US-12637513-B2 Method of treating cancer by administering an inhibitor of erythropoietin receptor activity comprising either erythropoietin receptor or erythropoietin protein IMMUNEDGE, INC. (US) 2026-05-26 US disclosed
WO-2026107052-A1 COMBINATION TREATMENTS USING EPIGENETIC INHIBITION AND SYNGRI-MEDIATED FRATAXIN EXPRESSION ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2026-05-21 WO disclosed
US-20260116986-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS IMMUNEDGE INC (US) 2026-04-30 US disclosed
US-12540189-B2 2026-02-03 US disclosed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US disclosed
CN-217443969-U Wireless inspection system for ship lock 南京洛普股份有限公司 2022-09-16 CN disclosed
US-20220257741-A1 COMBINATION THERAPY FOR CANCER IO BIOTECH APS (DK) 2022-08-18 US disclosed
US-20220127257-A1 SMALL MOLECULES UNIVERSITY OF DUNDEE (GB) 2022-04-28 US disclosed
WO-2022040798-A1 COMPOSITIONS AND METHODS FOR GENERATING HUMAN YOLK SAC-LIKE HEMATOPOIETIC CELLS UNIVERSITY HEALTH NETWORK (CA) 2022-03-03 WO disclosed
US-11261179-B2 Small molecules UNIVERSITY OF DUNDEE (GB) 2022-03-01 US disclosed
US-20220025324-A1 METHODS OF PRODUCING VENOUS ANGIOBLASTS AND SINUSOIDAL ENDOTHELIAL CELL-LIKE CELLS AND COMPOSITIONS THEREOF UNIVERSITY HEALTH NETWORK (CA) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, MPL, PRLHR EGLN2 146/4885EGLN1 503/4885HIF1AN 37/4885
US-20260027096-A1 PHD INHIBITORS HIF1AN, HIF1A, EGLN1 EGLN2 5/4885EGLN1 3/4885HIF1AN 1/4885
US-20220127257-A1 SMALL MOLECULES ADRM1, MDM2, UBE2B EGLN2 1797/4885EGLN1 1343/4885HIF1AN 1799/4885
US-12540189-B2 EPOR, MPL, JAK2 EGLN2 398/4885EGLN1 646/4885HIF1AN 119/4885
US-12637513-B2 Method of treating cancer by administering an inhibitor of erythropoietin receptor activity comprising either erythropoietin receptor or erythropoietin protein EPOR, MPL, CSF3R EGLN2 527/4885EGLN1 987/4885HIF1AN 122/4885
US-20260116986-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, STAT5A, JAK2 EGLN2 407/4885EGLN1 746/4885HIF1AN 289/4885
US-11261179-B2 Small molecules ADRM1, MDM2, UBE2B EGLN2 1797/4885EGLN1 1343/4885HIF1AN 1799/4885
US-20230201359-A1 MONOCYTE-SPECIFIC APTAMERS AND USES THEREOF FOR DELIVERING THERAPEUTIC AGENTS TO HEART FABP3, CD14, FABP1 EGLN2 3401/4885EGLN1 3840/4885HIF1AN 2259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.