Sugi Predict

Sugi Predict / Compounds / SCHEMBL29360613

SCHEMBL29360613

SCHEMBL29360613

COc1cc(C(=O)c2cn(S(=O)(=O)c3ccccc3)c(-c3ccccc3C(F)(F)F)n2)cc(OC)c1OC

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 17/20 0.51
▸ TUBB P07437 17/20 0.51
▸ TUBA3C P0DPH7 17/20 0.51
▸ TUBA1B P68363 17/20 0.51
▸ TUBA4A P68366 17/20 0.51
▸ TUBB4B P68371 17/20 0.51
▸ TUBB3 Q13509 17/20 0.51
▸ TUBB2A Q13885 17/20 0.51
▸ TUBB8 Q3ZCM7 17/20 0.51
▸ TUBA3E Q6PEY2 17/20 0.51
▸ TUBA1A Q71U36 17/20 0.51
▸ TUBA1C Q9BQE3 17/20 0.51
▸ TUBB6 Q9BUF5 17/20 0.51
▸ TUBB2B Q9BVA1 17/20 0.51
▸ TUBB1 Q9H4B7 17/20 0.51
▸ CA12 O43570 2/20 0.43
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CA9 Q16790 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL771330 1.00 TUBB4A (0.51) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL724399 0.86 TUBB4A (0.50) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL723708 0.85 TUBB4A (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL725068 0.83 TUBB4A (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29728502 0.82 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL726776 0.82 TUBB4A (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL725240 0.82 TUBB4A (0.53) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL724617 0.81 HSD11B1 (0.38) CA1CA2CA9
SCHEMBL771579 0.81 TUBB4A (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL724871 0.81 TUBB4A (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 — — US disclosed
US-12187720-B2 Compounds for treatment of cancer UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-07 — — US disclosed
US-11465987-B2 Compounds for treatment of cancer Oncternal Therapeutics, Inc. (US) 2022-10-11 — — US disclosed
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER Oncternal Therapeutics, Inc. (US) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187720-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 TUBB4A 296/4885TUBB 213/4885TUBA3C 1166/4885
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 TUBB4A 296/4885TUBB 213/4885TUBA3C 1166/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 TUBB4A 296/4885TUBB 213/4885TUBA3C 1166/4885
US-11465987-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 TUBB4A 296/4885TUBB 213/4885TUBA3C 1166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.