Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 6/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742254 | 1.00 | ACMSD (0.76) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL14252244 | 0.89 | ACMSD (0.76) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL412439 | 0.86 | ACMSD (1.00) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL505872 | 0.86 | ACMSD (0.71) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL10024262 | 0.85 | ACMSD (0.69) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL121427 | 0.83 | ACMSD (0.63) | ACMSDDHFRPTPN1MCL1AKR1C2 | |
| SCHEMBL31028186 | 0.83 | ACMSD (0.63) | ACMSDDHFRPTPN1MCL1AKR1C2 | |
| SCHEMBL28173338 | 0.83 | ACMSD (0.77) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL12878521 | 0.82 | ACMSD (0.66) | ACMSDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL2559727 | 0.82 | ACMSD (0.54) | ACMSDALDH1A1KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306297-A | Proteasome inhibitors and uses thereof | 康奈尔大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-108351169-B | Proteasome inhibitors and uses thereof | 康奈尔大学 | 2022-01-28 | — | — | CN | disclosed |