Cecropin A

Cecropin A

SCHEMBL29361111

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(C)C)C(C)C)[C@@H](C)CC

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.67
▸ NPY1R P25929 1/20 0.67
▸ NPY2R P49146 1/20 0.67
▸ NPY4R P50391 1/20 0.67
▸ NPY5R Q15761 1/20 0.67
▸ GLP1R P43220 13/20 0.67
▸ GIPR P48546 7/20 0.64
▸ CALCA P06881 2/20 0.64
▸ GCGR P47871 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28972123 0.98 KEAP1 (0.69) KEAP1NPY1RNPY2RNPY4RNPY5R
Cecropin Ad SCHEMBL29842479 0.97 NPY1R (0.68) KEAP1NPY1RNPY2RNPY4RNPY5R
SCHEMBL30495604 0.92 GLP1R (0.71) KEAP1NPY1RNPY2RNPY4RNPY5R
SCHEMBL31182815 0.92 NPY2R (0.73) KEAP1NPY1RNPY2RNPY4RNPY5R
SCHEMBL29949636 0.92 NPY1R (0.71) KEAP1NPY1RNPY2RNPY4RNPY5R
Cecropin B SCHEMBL29355118 0.92 KEAP1 (0.69) KEAP1GLP1RGCGR
SCHEMBL31182745 0.91 NPY1R (0.71) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL29412272 0.91 CXCR4 (0.66) KEAP1NPY1RNPY2RNPY4RNPY5R
SCHEMBL29352195 0.91 NPY2R (0.70) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL31182544 0.91 NPY1R (0.69) KEAP1NPY1RNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101236-A1 PEPTIDES SPECIFICALLY BINDING TO CCR8, AND USE THEREOF 경희대학교 산학협력단 2026-05-15 — — WO claimed
EP-4074831-B1 NOVEL POLYPEPTIDE, FUSION POLYPEPTIDE, AND ANTIBIOTIC AGAINST GRAM-NEGATIVE BACTERIA COMPRISING SAME LYSENTECH CO LTD (KR) 2026-01-21 — — EP claimed
EP-4677075-A2 TARGETING CELLS IN STRESSED GROWING CONDITIONS SNIPR Biome ApS (DK) 2026-01-14 — — EP claimed
US-20260000782-A1 ITGB2-MEDIATED DRUG DELIVERY SYSTEM TWINPIG BIOLAB INC. (KR) 2026-01-01 — — US claimed
US-20250228951-A1 NOVEL-PEPTIDE-BASED ANTICANCER IMMUNOTHERAPEUTIC AGENT TWINPIG BIOLAB INC. (KR) 2025-07-17 — — US claimed
CN-115925981-B Antibacterial peptide for specific targeting of gram-negative bacteria and application thereof 河南工业大学 2025-05-23 — — CN claimed
WO-2025106551-A1 HYDROGEL COMPOSITIONS COMPRISING SYNERGISTIC ANTIMICROBIAL PEPTIDES (AMPS) AND METHODS OF MAKING SAME ROWAN UNIVERSITY (US) 2025-05-22 — — WO claimed
CN-112689758-B Device and method for checking the effect of a drug on microorganisms 上海宜晟生物科技有限公司 2025-03-28 — — CN claimed
CN-119619105-A Analysis method of surface enhanced Raman spectrum three-dimensional code on complex system and application thereof 中国人民解放军陆军军医大学第一附属医院 2025-03-14 — — CN claimed
EP-4512411-A2 ITGB2-MEDIATED DRUG DELIVERY SYSTEM Twinpig Biolab, Inc. (KR) 2025-02-26 — — EP claimed
EP-4074831-A1 NOVEL POLYPEPTIDE, FUSION POLYPEPTIDE, AND ANTIBIOTIC AGAINST GRAM-NEGATIVE BACTERIA COMPRISING SAME Lysentech Co., Ltd. (KR) 2022-10-19 — — EP claimed
WO-2022204806-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2022-10-06 — — WO claimed
EP-3129044-B1 PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS LYSANDO AG (LI) 2022-09-07 — — EP claimed
CN-113384737-B Imbibition controlled-release antibacterial peptide hydrogel double-layer dressing and preparation method and application thereof 重庆理工大学 2022-08-23 — — CN claimed
CN-114747674-A Opening material for preventing lamb diarrhea and ewe mastitis 榆阳区畜牧技术推广站 2022-07-15 — — CN claimed
CN-114569488-A Antibacterial peptide modified nanocellulose hydrogel, preparation method and application thereof 宁波糖聚新材料有限责任公司 2022-06-03 — — CN claimed
CN-107636017-B Polypeptide-based shuttle agents for improving the efficiency of transduction of a polypeptide cargo into the cytoplasm of a target eukaryotic cell, uses thereof, and methods and kits related thereto 费尔丹生物公司 2022-05-31 — — CN claimed
WO-2022082315-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2022-04-28 — — WO claimed
WO-2022077121-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2022-04-21 — — WO claimed
CN-114106937-A Contact lens care solution 东南大学 2022-03-01 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000782-A1 ITGB2-MEDIATED DRUG DELIVERY SYSTEM ITGB8, ITGB2, ITGA8 KEAP1 4549/4885NPY1R 2099/4885NPY2R 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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