SCHEMBL28972123

SCHEMBL28972123

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(C)C)C(C)C)[C@@H](C)CC

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.69
▸ GLP1R P43220 12/20 0.68
▸ CALCA P06881 2/20 0.66
▸ NPY1R P25929 1/20 0.65
▸ NPY2R P49146 1/20 0.65
▸ NPY4R P50391 1/20 0.65
▸ NPY5R Q15761 1/20 0.65
▸ GIPR P48546 7/20 0.64
▸ GCGR P47871 1/20 0.64
▸ CXCR4 P61073 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cecropin A SCHEMBL29361111 0.98 KEAP1 (0.67) KEAP1GLP1RCALCANPY1RNPY2R
Cecropin Ad SCHEMBL29842479 0.95 NPY1R (0.68) KEAP1GLP1RCALCANPY1RNPY2R
Cecropin B SCHEMBL29355118 0.93 KEAP1 (0.69) KEAP1GLP1RGCGR
SCHEMBL29949636 0.91 NPY1R (0.71) KEAP1GLP1RCALCANPY1RNPY2R
SCHEMBL29922501 0.91 GLP1R (0.76) KEAP1GLP1RGIPRGCGR
SCHEMBL29922531 0.90 GLP1R (0.76) KEAP1GLP1RGIPRGCGR
SCHEMBL30495604 0.90 GLP1R (0.71) KEAP1GLP1RNPY1RNPY2RNPY4R
SCHEMBL31182815 0.90 NPY2R (0.73) KEAP1GLP1RNPY1RNPY2RNPY4R
SCHEMBL29444962 0.90 KEAP1 (0.69) KEAP1GLP1RNPY1RNPY2RNPY4R
SCHEMBL29391164 0.90 GLP1R (0.65) KEAP1GLP1RCALCANPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115487114-B Antibacterial peptide composition, acne-removing cream containing antibacterial peptide composition and preparation method of acne-removing cream 广东粤港澳大湾区黄埔材料研究院 2023-10-03 — — CN claimed
US-RE50618-E1 Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same PHARMAIN CORPORATION (US) 2025-10-07 — — US disclosed
CN-116785447-B Novel conjugates of montelukast and peptides 艾缇亚(上海)制药有限公司 2024-11-22 — — CN disclosed
CN-117487750-B Use of NK cells in the treatment of immune related disorders 青岛西凯生物技术有限公司 2024-06-21 — — CN disclosed
CN-117487750-A Use of NK cells in the treatment of immune related disorders 青岛西凯生物技术有限公司 2024-02-02 — — CN disclosed
CN-115487114-B Antibacterial peptide composition, acne-removing cream containing antibacterial peptide composition and preparation method of acne-removing cream 广东粤港澳大湾区黄埔材料研究院 2023-10-03 — — CN disclosed
EP-3317294-B1 STABILIZED ANTI-MICROBIAL PEPTIDES DANA FARBER CANCER INST INC (US) 2023-03-15 — — EP disclosed
EP-3519426-B1 ANTIMICROBIAL PEPTIDES COMPRISING EPSILON LYSINE RESIDUES SINGAPORE HEALTH SERV PTE LTD (SG) 2023-02-15 — — EP disclosed
CN-115487114-A Antibacterial peptide composition, acne-removing cream containing antibacterial peptide composition and preparation method of acne-removing cream 广东粤港澳大湾区黄埔材料研究院 2022-12-20 — — CN disclosed
US-11396531-B2 Antimicrobial peptides comprising epsilon lysine residues SINGAPORE HEALTH SERVICES PTE LTD (SG) 2022-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11396531-B2 Antimicrobial peptides comprising epsilon lysine residues ARG1, MYADM, ARG2 KEAP1 4194/4885GLP1R 452/4885CALCA 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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