Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 2/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 2/20 | 0.37 |
| ▸ | CCNH | P51946 | 2/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029073 | 1.00 | BTK (0.41) | BTKCCNKCDK12CCNT1CCNE1 | |
| SCHEMBL29364621 | 0.90 | BTK (0.43) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL26717704 | 0.90 | BTK (0.43) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL25028882 | 0.90 | BTK (0.43) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL26719030 | 0.90 | BTK (0.43) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL25028656 | 0.88 | NFATC1 (0.40) | BTKCCNKCDK12CCNT1CCNE1 | |
| SCHEMBL29362053 | 0.88 | BTK (0.44) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL25029306 | 0.88 | BTK (0.42) | BTKNFATC1GSK3BDYRK1ACYP11B1 | |
| SCHEMBL29364633 | 0.88 | NFATC1 (0.40) | BTKCCNKCDK12CCNT1CCNE1 | |
| SCHEMBL25028902 | 0.88 | BTK (0.44) | BTKNFATC1GSK3BDYRK1ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |