Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25C | P30307 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | APEX1 | P27695 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917644 | 0.89 | MEN1 (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL29369543 | 0.89 | MEN1 (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL4247040 | 0.84 | MEN1 (0.75) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL1916880 | 0.78 | CDC25C (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL6080522 | 0.78 | MEN1 (0.68) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL6434785 | 0.76 | CDC25C (0.61) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3153190 | 0.76 | CDC25C (0.67) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3158326 | 0.75 | CDC25C (0.65) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3143117 | 0.74 | KCNH2 (0.64) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL1917318 | 0.74 | CDC25C (1.00) | CDC25CMEN1THRBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119700983-A | Application of UBR5 in preparation of medicines for treating pigment dermatosis | 中南大学湘雅医院 | 2025-03-28 | — | — | CN | claimed |
| CN-119700983-A | Application of UBR5 in preparation of medicines for treating pigment dermatosis | 中南大学湘雅医院 | 2025-03-28 | — | — | CN | disclosed |
| US-20240110230-A1 | BIOMARKERS FOR CANCER TREATMENT | FOUNDATION MEDICINE, INC. (US) | 2024-04-04 | — | — | US | disclosed |
| EP-4291902-A2 | BIOMARKERS FOR CANCER TREATMENT | Foundation Medicine, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022174234-A2 | BIOMARKERS FOR CANCER TREATMENT | FOUNDATION MEDICINE, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| WO-2022018667-A1 | COMBINATION THERAPIES USING CDK2 AND CDC25A INHIBITORS | PFIZER INC. (US) | 2022-01-27 | — | — | WO | disclosed |