Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25C | P30307 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362116 | 0.76 | CDC25C (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL1917644 | 0.76 | MEN1 (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL29369543 | 0.76 | MEN1 (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3143117 | 0.74 | KCNH2 (0.64) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL4247040 | 0.74 | MEN1 (0.75) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL9628028 | 0.72 | KCNH2 (0.74) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3158326 | 0.72 | CDC25C (0.65) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL1916880 | 0.71 | CDC25C (1.00) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL3153190 | 0.71 | CDC25C (0.67) | CDC25CMEN1THRBAPEX1RECQL | |
| SCHEMBL13897015 | 0.70 | KCNH2 (0.72) | CDC25CMEN1THRBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |