Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CDC25C | P30307 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247040 | 0.93 | MEN1 (0.75) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL1917644 | 0.82 | MEN1 (1.00) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL29369543 | 0.82 | MEN1 (1.00) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL1917276 | 0.81 | CDC25C (0.78) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL1916880 | 0.79 | CDC25C (1.00) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL29362116 | 0.78 | CDC25C (1.00) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL3158326 | 0.69 | CDC25C (0.65) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL6434785 | 0.69 | CDC25C (0.61) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL1917318 | 0.69 | CDC25C (1.00) | MEN1KMT2ATHRBAPEX1RECQL | |
| SCHEMBL1917474 | 0.67 | CDC25C (1.00) | MEN1KMT2ATHRBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154933-A1 | Inhibitors of Cdc25 phosphatases | SCRAS | 2006-07-13 | — | — | US | claimed |
| US-20060154933-A1 | Inhibitors of Cdc25 phosphatases | SCRAS | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154933-A1 | Inhibitors of Cdc25 phosphatases | CDC25A, CDC25C, CDC25B | MEN1 1858/4885KMT2A 1728/4885THRB 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.