Sugi Predict

Sugi Predict / Compounds / SCHEMBL293626

SCHEMBL293626

SCHEMBL293626

CC(C)(C)OC(=O)N1CC[CH]CC1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ HPGD P15428 1/20 0.49
▸ GPR119 Q8TDV5 3/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ EPHX1 P07099 1/20 0.46
▸ MAPT P10636 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ PTPN2 P17706 1/20 0.45
▸ PTPN1 P18031 1/20 0.45
▸ PTPN6 P29350 1/20 0.45
▸ EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25250236 0.98 USP2 (0.56) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL27906090 0.93 USP2 (0.51) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL2197203 0.93 USP2 (0.51) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL294179 0.88 USP2 (0.50) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL4773530 0.88 USP2 (0.58) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL698803 0.84 USP2 (0.69) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL18294 0.84 USP2 (0.69) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL4209805 0.84 USP2 (0.44) USP2SMN1; SMN2HPGDGPR119MEN1
SCHEMBL4195097 0.82 KDM4E (0.48) HPGDGPR119RECQLEPHX1MAPT
SCHEMBL15624094 0.81 USP2 (0.51) USP2SMN1; SMN2HPGDGPR119MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197888-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2024-06-20 — — US claimed
US-20240174643-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2024-05-30 — — US claimed
EP-4355741-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS Biotheryx, Inc. (US) 2024-04-24 — — EP claimed
CN-117794923-A Benzodioxane compound, and preparation method and application thereof 南京红云生物科技有限公司 2024-03-29 — — CN claimed
CN-117720403-A Preparation method of asymmetric ketone compound 大连理工大学 2024-03-19 — — CN claimed
US-20230348453-A1 HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2023-11-02 — — US claimed
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2023-10-26 — — US claimed
CN-114277389-B Method for synthesizing quinoline derivative by utilizing pyridinium photoelectrocatalysis Minisci reaction 齐鲁工业大学 2023-09-19 — — CN claimed
CN-113004278-B Bicyclic heterocycles as FGFR inhibitors 因赛特控股公司 2023-07-21 — — CN claimed
WO-2023113086-A1 SALT COMPOUND, AND QUENCHER AND PHOTORESIST COMPOSITION COMPRISING SAME 주식회사 동진쎄미켐 2023-06-22 — — WO claimed
US-6326359-B1 PURINE DERIVATIVES PFIZER INC 2001-12-04 — — US claimed
EP-1121372-A1 ADENINE DERIVATIVES Pfizer Limited (GB) 2001-08-08 — — EP claimed
US-6255491-B1 CHEMICAL INTERMEDIATES SUCH AS 1-(SUBSTITUTED), 4-ARYL, 5-(3-N,N-DISUBSTITUTED AMINO-1-PROPENONE) IMIDAZOLE, USEFUL FOR MAKING 5-PYRIMIDINYL IMIDAZOLES SMITHKLINE BEECHAM CORPORATION 2001-07-03 — — US claimed
CN-1064362-C Pyrimido [5,4-D] pyrimidines, medicaments containing these compounds, their use and process for their production THOMAE GMBH DR K (DE) 2001-04-11 — — CN claimed
WO-2001005783-A1 BRADYKININ B1 RECEPTOR ANTAGONISTS PHARMACOPEIA, INC. (US) 2001-01-25 — — WO claimed
US-6100399-A Synthesis for 4-aryl-5-pyrimidine imidazole substituted compounds SMITHKLINE BEECHAM CORPORATION (US) 2000-08-08 — — US claimed
WO-2000023457-A1 ADENINE DERIVATIVES PFIZER LIMITED (GB) 2000-04-27 — — WO claimed
CN-1212694-A Pyrimido [5,4-D] pyrimidines, medicaments containing these compounds, their use and process for their production THOMAE GMBH DR K (DE) 1999-03-31 — — CN claimed
US-5869660-A Process of preparing imidazole compounds SMITHKLINE BEECHAM CORPORATION (US) 1999-02-09 — — US claimed
US-5821240-A ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS DR. KARL THOMAE GMBH (DE) 1998-10-13 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CSNK1A1, CSNK1D, CSNK1G1 USP2 1045/4885SMN1; SMN2 2039/4885HPGD 488/4885
US-20240197888-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS SOS1, SOS2, SOST USP2 160/4885SMN1; SMN2 93/4885HPGD 4013/4885
US-20230348453-A1 HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF ABL1, PRKDC, PRKACA USP2 2456/4885SMN1; SMN2 4155/4885HPGD 4581/4885
US-20240174643-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS SOS1, SOS2, SOST USP2 153/4885SMN1; SMN2 102/4885HPGD 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.