Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.61 |
| ▸ | F2 | P00734 | 4/20 | 0.60 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.59 |
| ▸ | MC4R | P32245 | 1/20 | 0.59 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.58 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.58 |
| ▸ | CALCR | P30988 | 2/20 | 0.58 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262245 | 0.91 | MC4R (0.62) | APLNRF2C5AR1MC4RNMUR2 | |
| SCHEMBL30576961 | 0.89 | RAMP3 (0.59) | APLNRC5AR1CALCRRAMP3 | |
| SCHEMBL31182616 | 0.88 | RAMP3 (0.63) | F2CALCRRAMP3 | |
| SCHEMBL30058340 | 0.88 | F2 (0.63) | APLNRF2C5AR1CALCRRAMP3 | |
| SCHEMBL29521314 | 0.88 | APLNR (0.61) | APLNRF2C5AR1NMUR2NMUR1 | |
| SCHEMBL30423484 | 0.88 | GLP1R (0.60) | CALCRRAMP3 | |
| SCHEMBL30262247 | 0.88 | C5AR1 (0.62) | APLNRF2C5AR1MC4RNMUR2 | |
| SCHEMBL30512520 | 0.87 | F2 (0.61) | APLNRF2C5AR1MC4RNMUR2 | |
| SCHEMBL31182896 | 0.87 | CALCR (0.66) | CALCR | |
| SCHEMBL31182654 | 0.87 | NPY2R (0.66) | C5AR1CALCRRAMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089719-A1 | CONSTRUCTS TARGETING LABYRINTHIN OR A PORTION THEREOF AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS (USA) LIMITED (US) | 2022-03-24 | — | — | US | disclosed |
| CN-113993892-A | Constructs targeting labyrinth proteins or parts thereof and uses of said constructs | 莱比锡免疫治疗(美国)有限公司 | 2022-01-28 | — | — | CN | disclosed |