SCHEMBL30262245

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	1/20	0.62

▸	RAMP3	O60896	1/20	0.62

▸	CALCR	P30988	1/20	0.62

▸	F2	P00734	4/20	0.62

▸	C5AR1	P21730	1/20	0.61

▸	NMUR2	Q9GZQ4	3/20	0.60

▸	NMUR1	Q9HB89	3/20	0.60

▸	NPY2R	P49146	7/20	0.59

▸	NPY4R	P50391	7/20	0.59

▸	NPY5R	Q15761	7/20	0.59

▸	NPY1R	P25929	5/20	0.59

▸	APLNR	P35414	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29362632	0.91	APLNR (0.61)	MC4RRAMP3CALCRF2C5AR1
SCHEMBL30436896	0.90	CALCR (0.68)	MC4RRAMP3CALCRC5AR1NPY2R
SCHEMBL31174210	0.89	MC4R (0.60)	MC4RRAMP3CALCRF2C5AR1
SCHEMBL31182654	0.89	NPY2R (0.66)	RAMP3CALCRC5AR1NPY2RNPY4R
SCHEMBL31182616	0.89	RAMP3 (0.63)	RAMP3CALCRF2NPY2RNPY4R
SCHEMBL30432646	0.89	CALCR (0.67)	CALCRF2C5AR1NPY2RNPY4R
SCHEMBL30607329	0.89	F2 (0.68)	RAMP3CALCRF2C5AR1NMUR2
SCHEMBL30726629	0.88	F2 (0.63)	MC4RCALCRF2C5AR1NPY2R
SCHEMBL29742947	0.88	F2 (0.62)	MC4RCALCRF2C5AR1NPY2R
SCHEMBL30576961	0.88	RAMP3 (0.59)	RAMP3CALCRC5AR1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed