SCHEMBL29362811

SCHEMBL29362811

Cc1cccc(-c2ccccc2O)c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.62
TRPA1 O75762 2/20 0.62
GAA P10253 2/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
HSD17B10 Q99714 4/20 0.44
HPGD P15428 4/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 4/20 0.44
TP53 P04637 2/20 0.44
BCL2L1 Q07817 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 5/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 3/20 0.43
NFKB1 P19838 3/20 0.43
TSHR P16473 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982858 1.00 ATM (0.62) ATMTRPA1GAAMGAMSI
SCHEMBL13139659 0.88 TRPA1 (0.73) ATMTRPA1GAAMGAMSI
SCHEMBL29113726 0.88 ALDH1A1 (0.50) ATMTRPA1GAAMGAMSI
SCHEMBL930935 0.86 TRPA1 (0.54) ATMTRPA1GAAMGAMSI
SCHEMBL5589909 0.84 TRPA1 (0.60) ATMTRPA1GAAMGAMSI
SCHEMBL27572785 0.84 ATM (0.48) ATMTRPA1GAAMGAMSI
SCHEMBL674991 0.84 ALDH1A1 (0.67) ATMTRPA1GAAMGAMSI
SCHEMBL758202 0.83 HPGD (0.52) ATMTRPA1GAAMGAMSI
SCHEMBL31337248 0.83 HPGD (0.52) ATMTRPA1GAAMGAMSI
SCHEMBL31069812 0.83 TRPA1 (0.58) ATMTRPA1GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116194552-A Cyclic phosphazene compounds having oxaphosphaphenanthrene-containing ring structure 株式会社伏见制药所 2023-05-30 CN disclosed
WO-2022019021-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE 株式会社伏見製薬所 2022-01-27 WO disclosed