Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23825685 | 0.86 | NOTUM (0.54) | NOTUMCYP1A2IL2 | |
| SCHEMBL7290389 | 0.86 | NOTUM (0.54) | NOTUMCYP1A2 | |
| SCHEMBL28614218 | 0.85 | NOTUM (0.46) | NOTUMCYP1A2 | |
| SCHEMBL31336425 | 0.79 | NOTUM (0.50) | NOTUMCYP1A2 | |
| SCHEMBL29366780 | 0.79 | NOTUM (0.50) | NOTUMCYP1A2 | |
| SCHEMBL29366281 | 0.78 | BRD4 (0.49) | NOTUMCYP1A2IL2 | |
| SCHEMBL31335498 | 0.78 | NOTUM (0.57) | NOTUMCYP1A2 | |
| SCHEMBL23825802 | 0.78 | NOTUM (0.57) | NOTUMCYP1A2 | |
| Hydrochloric Acid SCHEMBL23827016 | 0.77 | NOTUM (0.56) | NOTUMCYP1A2 | |
| SCHEMBL23825566 | 0.76 | NOTUM (0.55) | NOTUMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | claimed |
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | PIM1, PIM3, PIM2 | NOTUM 1103/4885CYP1A2 1082/4885IL2 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.