Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363056 | 0.86 | NOTUM (0.51) | NOTUMCYP1A2 | |
| SCHEMBL29366281 | 0.80 | BRD4 (0.49) | NOTUMCYP1A2CTSD | |
| SCHEMBL28622786 | 0.80 | NOTUM (0.46) | NOTUML3MBTL1CYP1A2KDM4ELMNA | |
| SCHEMBL28614218 | 0.80 | NOTUM (0.46) | NOTUMCYP1A2CTSD | |
| SCHEMBL30615060 | 0.78 | ATR (0.53) | L3MBTL1ATR | |
| SCHEMBL3180689 | 0.77 | L3MBTL1 (0.61) | L3MBTL1 | |
| SCHEMBL524005 | 0.77 | NPSR1 (0.54) | L3MBTL1CYP1A2KDM4ELMNA | |
| SCHEMBL1272211 | 0.76 | HDAC1 (0.48) | L3MBTL1CYP1A2 | |
| SCHEMBL15110089 | 0.76 | HPN (0.48) | L3MBTL1 | |
| SCHEMBL24000187 | 0.75 | ROCK2 (0.63) | CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981531-A | FOR INHIBITING PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| US-5760057-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0632016-B1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LTD (GB) | 1997-04-09 | — | — | EP | disclosed |
| US-5612373-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1997-03-18 | — | — | US | disclosed |
| WO-1995000472-A1 | 1,2 DIACYLATED HYDRAZINE DERIVATIVES AND THEIR USE AS ALL ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |
| EP-0632016-A1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |