Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 2/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25027526 | 1.00 | GSK3B (0.47) | GSK3BDYRK1ANFATC1PDE1BPDE1A | |
| SCHEMBL25028765 | 0.83 | CCNT1 (0.52) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| SCHEMBL26715948 | 0.81 | PDE1B (0.45) | PDE1BPDE1APDE1CTTKBRD4 | |
| SCHEMBL26719386 | 0.81 | PDE1B (0.45) | PDE1BPDE1APDE1CTTKBRD4 | |
| SCHEMBL26718510 | 0.81 | DYRK1A (0.45) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| SCHEMBL26719137 | 0.79 | GSK3B (0.45) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| SCHEMBL25029171 | 0.79 | DYRK1A (0.58) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| SCHEMBL29364491 | 0.79 | DYRK1A (0.58) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| Trifluoroacetic Acid SCHEMBL29364340 | 0.76 | CCNT1 (0.51) | GSK3BDYRK1ANFATC1CDK2CDK9 | |
| SCHEMBL25028830 | 0.76 | DYRK1A (0.55) | GSK3BDYRK1ANFATC1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |