Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 13/20 | 0.51 |
| ▸ | CCNK | O75909 | 13/20 | 0.51 |
| ▸ | CDK9 | P50750 | 13/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 13/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.51 |
| ▸ | CDK2 | P24941 | 12/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.41 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 7/20 | 0.41 |
| ▸ | CCNH | P51946 | 7/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028765 | 0.91 | CCNT1 (0.52) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29363458 | 0.84 | CCNT1 (0.59) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29363835 | 0.84 | CCNT1 (0.46) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29361498 | 0.80 | CCNT1 (0.42) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL25028778 | 0.79 | CCNT1 (0.53) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29361385 | 0.79 | CCNT1 (0.53) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29361361 | 0.79 | CCNT1 (0.48) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29005531 | 0.79 | HRH4 (0.41) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL25247543 | 0.77 | GSK3B (0.43) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Trifluoroacetic Acid SCHEMBL29363990 | 0.77 | GSK3B (0.43) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |