Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242591 | 1.00 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL6017355 | 0.86 | TDP1 (0.54) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL29361610 | 0.85 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL30798461 | 0.85 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL4556786 | 0.85 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL4074618 | 0.85 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL4034951 | 0.84 | TSHR (0.56) | L3MBTL1KDM4EPOLBATMALDH1A1 | |
| SCHEMBL22912507 | 0.83 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL16790454 | 0.83 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL21957938 | 0.82 | TDP1 (0.50) | TDP1L3MBTL1PKMMAP2K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |