Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074618 | 1.00 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL6017355 | 0.88 | TDP1 (0.54) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL17714455 | 0.87 | TDP1 (0.50) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL4556786 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL29361610 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL20086999 | 0.85 | L3MBTL1 (0.58) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL844745 | 0.85 | TSHR (0.59) | L3MBTL1ALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL22912507 | 0.85 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL29363643 | 0.85 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E | |
| SCHEMBL16790454 | 0.85 | TDP1 (0.51) | TDP1L3MBTL1PKMMAP2K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |