Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12609562 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL31546825 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL30847846 | 0.81 | CHRNB2 (0.53) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL1481609 | 0.81 | CHRNB2 (0.53) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL1622637 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL1622639 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL21354925 | 0.78 | CHRNB2 (0.54) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL1962531 | 0.78 | KMT2A (0.51) | CHRNB2CHRNA3CHRNA7CHRNA4CHRNB4 | |
| SCHEMBL24746466 | 0.76 | DRD2 (0.47) | — | |
| SCHEMBL23517959 | 0.76 | CHRNB2 (0.33) | CHRNB2CHRNA4KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954831-A | Pyrimidopyrazoles, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |