Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 3/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029103 | 1.00 | MBOAT4 (0.36) | MBOAT4LRRK2AAK1KCNJ5KCNJ3 | |
| SCHEMBL26180189 | 0.90 | AAK1 (0.35) | MBOAT4LRRK2AAK1NFATC1GSK3B | |
| Water SCHEMBL25261801 | 0.82 | GSK3B (0.47) | MBOAT4NFATC1GSK3BDYRK1ARET | |
| SCHEMBL29361564 | 0.82 | GSK3B (0.47) | MBOAT4NFATC1GSK3BDYRK1ARET | |
| SCHEMBL25029318 | 0.82 | NFATC1 (0.32) | LRRK2AAK1NFATC1GSK3BDYRK1A | |
| SCHEMBL25029089 | 0.82 | GSK3B (0.47) | MBOAT4NFATC1GSK3BDYRK1ARET | |
| SCHEMBL29364692 | 0.80 | NFATC1 (0.32) | NFATC1GSK3BDYRK1A | |
| SCHEMBL25218789 | 0.80 | NFATC1 (0.32) | NFATC1GSK3BDYRK1A | |
| SCHEMBL29361374 | 0.73 | BTK (0.46) | — | |
| SCHEMBL25029338 | 0.73 | BTK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |