Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218789 | 1.00 | NFATC1 (0.32) | NFATC1GSK3BDYRK1ATTKMAPK8 | |
| SCHEMBL25029318 | 0.85 | NFATC1 (0.32) | NFATC1GSK3BDYRK1A | |
| SCHEMBL29361278 | 0.83 | DYRK1A (0.49) | NFATC1GSK3BDYRK1A | |
| SCHEMBL25029081 | 0.83 | DYRK1A (0.49) | NFATC1GSK3BDYRK1A | |
| SCHEMBL26180189 | 0.82 | AAK1 (0.35) | NFATC1GSK3BDYRK1A | |
| SCHEMBL25029103 | 0.80 | MBOAT4 (0.36) | NFATC1GSK3BDYRK1A | |
| SCHEMBL29364371 | 0.80 | MBOAT4 (0.36) | NFATC1GSK3BDYRK1A | |
| SCHEMBL26180175 | 0.74 | MAPK1 (0.32) | — | |
| SCHEMBL26180157 | 0.72 | GSK3B (0.41) | NFATC1GSK3BDYRK1A | |
| SCHEMBL29361374 | 0.71 | BTK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |